In 2006, US scientists published a landmark study that linked lower levels of a gene known as PCSK9 to lower rates of heart disease. Researchers then sought to test the thesis by identifying subjects with a rare mutation that resulted in even lower levels of PSCK9. Just two were discovered, including a young woman living in South Africa. The discovery allowed drug manufacturers to produce what became Praluent, the first FDA-approved cholesterol-lowering drug of the 21st Century, which would be ...
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Added September 26, 2019